英文名稱 | Ropivacaine mesylate |
---|---|
中文名稱 | 甲磺酸羅哌卡因 |
CAS號 | 854056-07-8 |
分子式 | C17H26N2O·CH4O3S |
分子量 | 370.51 | 274.41 |
外觀 | White to off-white powder |
儲存條件 | 4°C, sealed storage, away from moisture |
英文名稱 | Ropivacaine mesylate |
---|---|
中文名稱 | 甲磺酸羅哌卡因 |
CAS號 | 854056-07-8 |
分子式 | C17H26N2O·CH4O3S |
分子量 | 370.51 | 274.41 |
外觀 | White to off-white powder |
儲存條件 | 4°C, sealed storage, away from moisture |
Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane.
PMID: 25617901 PMCID: PMC4305322 DOI: 10.1371/journal.pone.0117321
PMID: 30822427 DOI: 10.1016/j.lfs.2019.02.053