英文名稱 | Ropivacaine |
---|---|
中文名稱 | 羅哌卡因 |
CAS號 | 84057-95-4 |
分子式 | C17H26N2O |
分子量 | 274.40 |
外觀 | White to off-white powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | Ropivacaine |
---|---|
中文名稱 | 羅哌卡因 |
CAS號 | 84057-95-4 |
分子式 | C17H26N2O |
分子量 | 274.40 |
外觀 | White to off-white powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is used for the research of neuropathic pain management.
PMID: 16392884 DOI: 10.2165/00003495-200565180-00013
PMID: 30822427 DOI: 10.1016/j.lfs.2019.02.053
PMID: 23797625 DOI: 10.1007/s00540-013-1661-1
PMID: 25617901 PMCID: PMC4305322 DOI: 10.1371/journal.pone.0117321