英文名稱 | Anti-Human CD3xClaudin18.2 Bispecific Antibody ( Gresonitamab; AMG 910; ) |
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中文名稱 | 格瑞妥單抗 |
CAS號(hào) | 2413817-97-5 |
儲(chǔ)存條件 | Shipping with blue ice. |
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英文名稱 | Anti-Human CD3xClaudin18.2 Bispecific Antibody ( Gresonitamab; AMG 910; ) |
---|---|
中文名稱 | 格瑞妥單抗 |
CAS號(hào) | 2413817-97-5 |
儲(chǔ)存條件 | Shipping with blue ice. |
Gresonitamab is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody that targets CD3-positive T cells and CLDN18.2-expressing tumor cells, with potential immunostimulatory and antineoplastic activities. It activates and proliferates T-cells, leading to the lysis of CLDN18.2-expressing tumor cells, Gresonitamab can be used for the research of adenocarcinoma.
Claudin18.2 is a novel molecular biomarker for tumor-targeted immunotherapy.
PMCID: PMC9153115 PMID: 35642043