英文名稱 | Abatacept (Synonyms: CTLA4lg; BMS-188667) |
---|---|
中文名稱 | 阿巴西普 |
CAS號 | 332348-12-6 |
外觀 | Colorless to light yellow liquid |
儲存條件 | -20°C for 3 years |
英文名稱 | Abatacept (Synonyms: CTLA4lg; BMS-188667) |
---|---|
中文名稱 | 阿巴西普 |
CAS號 | 332348-12-6 |
外觀 | Colorless to light yellow liquid |
儲存條件 | -20°C for 3 years |
Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein drug for autoimmune diseases.
Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency.
PMID: 31238161 PMCID: PMC6842687 DOI: 10.1016/j.jaip.2019.06.011
PMID: 26473409 DOI: 10.1002/art.39470
PMID: 24233383 PMCID: PMC3947259 DOI: 10.1007/s10928-013-9341-1