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基本信息

英文名稱	Anti-Human VEGFAxANGPT2 (Faricimab; RG7716)
中文名稱	法瑞西單抗
CAS號	1607793-29-2
儲存條件	store at -20°C

產品詳情

Faricimab is a pioneering humanized bispecific antibody that targets both VEGF-A and Ang-2, offering a dual inhibition approach for retinal diseases like DME and nAMD. By inhibiting VEGF-A, it reduces endothelial cell proliferation and vascular permeability, while blocking Ang-2 is believed to enhance vascular stability and counteract VEGF-A effects. Faricimab has demonstrated a significant reduction in annual injections compared to other anti-VEGF treatments, with a comparable efficacy and safety profile, positioning it as a valuable treatment option for patients with retinal diseases.

PMID: 38233896 PMCID: PMC10795384 DOI: 10.1186/s40942-024-00525-9

PMID: 37936232 PMCID: PMC10631190 DOI: 10.1186/s40942-023-00507-3

PMID: 37377777 PMCID: PMC10291265 DOI: 10.3389/fncel.2023.1192464

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法瑞西單抗

Anti-Human VEGFAxANGPT2 (Faricimab; RG7716)

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