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庫存

目錄價(jià)

會(huì)員專享價(jià)

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基本信息

英文名稱	Anti-Human PD-1xCTLA-4 Bispecific Antibody(Cadonilimab)
中文名稱	卡度尼利單抗
CAS號(hào)	2394841-59-7
儲(chǔ)存條件	-80°C for one-year storage. Avoid repeated freeze-thaw.

產(chǎn)品詳情

Cadonilimab is a pioneering bispecific antibody targeting PD-1 and CTLA-4,it blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC).

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