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首頁(yè) > 產(chǎn)品目錄 > 信號(hào)通路 > Metabolism (代謝) > PCSK9 > 依洛尤單抗; 依伏庫(kù)單抗

依洛尤單抗; 依伏庫(kù)單抗

Anti-Human PCSK9 Monoclonal Antibody(Evolocumab); AMG 145

產(chǎn)品編號(hào):CLA1013 CAS No.:1256937-27-5 MDLNo: 分子式: 分子量:
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專(zhuān)享價(jià) 數(shù)量
1 mg 3-5days ¥3000.00 登錄后可見(jiàn)
- +
5 mg 3-5days ¥12500.00 登錄后可見(jiàn)
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10 mg 3-5days ¥20000.00 登錄后可見(jiàn)
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50 mg 3-5days ¥80000.00 登錄后可見(jiàn)
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100 mg 3-5days ¥125000.00 登錄后可見(jiàn)
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基本信息
英文名稱(chēng) Anti-Human PCSK9 Monoclonal Antibody(Evolocumab); AMG 145
中文名稱(chēng)依洛尤單抗; 依伏庫(kù)單抗
CAS號(hào)1256937-27-5
外觀Colorless to light yellow (Solution)
儲(chǔ)存條件Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
產(chǎn)品詳情

Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation.

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