PIK-90 ; CAS: 677338-12-4

規(guī)格	庫存	目錄價	會員專享價	數(shù)量
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規(guī)格

庫存

目錄價

會員專享價

數(shù)量

暫無牌價信息，您可以發(fā)送詢價，我們會盡快給你回復(fù)。

基本信息

英文名稱	PIK-90
中文名稱	N-(7,8-二甲氧基-2,3-二氫咪唑并[1,2-c]喹唑啉-5-基)煙酰胺
CAS號	677338-12-4
分子式	C18H17N5O3
分子量	351.36
MDL	MFCD12910483
外觀	Off-white to yellow powder
儲存條件	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

產(chǎn)品詳情

PIK-90 is recognized as a potent inhibitor of both DNA-PK and PI3K, demonstrating its inhibitory effects on the p110α, p110γ, and DNA-PK with respective IC50 values of 11, 18, and 13 nM. This compound plays a significant role in the realm of molecular biology and cancer research, where its ability to target these key enzymes is of paramount importance.

相關(guān)文獻(xiàn)

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.

PMID: 16647110 PMCID: PMC2946820 DOI: 10.1016/j.cell.2006.03.035

PMID: 19318683 PMCID: PMC4580965 DOI: 10.1182/blood-2008-06-165068

PMID: 22802621 PMCID: PMC3411950 DOI: 10.1073/pnas.1202492109

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N-(7,8-二甲氧基-2,3-二氫咪唑并[1,2-c]喹唑啉-5-基)煙酰胺

PIK-90

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