英文名稱 | Golvatinib | E-7050 |
---|---|
中文名稱 | Golvatinib | E-7050 |
CAS號 | 928037-13-2 |
分子式 | C33H37F2N7O4 |
分子量 | 633.69 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Golvatinib | E-7050 |
---|---|
中文名稱 | Golvatinib | E-7050 |
CAS號 | 928037-13-2 |
分子式 | C33H37F2N7O4 |
分子量 | 633.69 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Golvatinib (E-7050) is a potent dual inhibitor of both c-Met and VEGFR2 kinases with IC50s of 14 and 16 nM, respectively.
PMID: 19832844 PMCID: PMC11159146 DOI: 10.1111/j.1349-7006.2009.01343.x
PMID: 22317763 DOI: 10.1158/1078-0432.CCR-11-1171