Aliskiren Hemifumarate (Synonyms: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate)； CAS: 173334-58-2

規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專(zhuān)享價(jià)	數(shù)量
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規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專(zhuān)享價(jià)

數(shù)量

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基本信息

英文名稱(chēng)	Aliskiren Hemifumarate (Synonyms: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate)
中文名稱(chēng)	(2S,4S,5S,7S)-5-氨基-N-(3-氨基-2,2-二甲基-3-氧代丙基)-4-羥基-2-異丙基-7-(4-甲氧基-3-( 3-甲氧基丙氧基)芐基)-8-甲基壬酰胺半富馬酸鹽；阿利克侖半富馬酸鹽
CAS號(hào)	173334-58-2
分子式	C34H57N3O10
分子量	667.83
MDL	MFCD10566724
外觀	White to off-white powder
儲(chǔ)存條件	4°C, sealed storage, away from moisture

產(chǎn)品詳情

Aliskiren hemifumarate (CGP 60536; CGP60536B; SPP 100) is an orally active, selective renin inhibitor with an IC50 of 1.5 nM. It is utilized in research pertaining to hypertension, cardiovascular diseases, and cancer cachexia.As a direct renin inhibitor, aliskiren targets the renin-angiotensin-aldosterone system (RAAS), a key pathway in blood pressure regulation. Its role in hypertension management is significant, offering an alternative to traditional antihypertensive medications. Additionally, aliskiren's potential impact on cardiovascular health and cancer cachexia is under investigation, highlighting its broad research applications.

相關(guān)文獻(xiàn)

Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.

https://doi.org/10.1021/ml300168e

PMID: 25070349 DOI: 10.1177/1470320314528364

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CL3027A

(2S,4S,5S,7S)-5-氨基-N-(3-氨基-2,2-二甲基-3-氧代丙基)-4-羥基-2-異丙基-7-(4-甲氧基-3-( 3-甲氧基丙氧基)芐基)-8-甲基壬酰胺半富馬酸鹽；阿利克侖半富馬酸鹽

173334-58-2 98+%

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(2S,4S,5S,7S)-5-氨基-N-(3-氨基-2,2-二甲基-3-氧代丙基)-4-羥基-2-異丙基-7-(4-甲氧基-3-( 3-甲氧基丙氧基)芐基)-8-甲基壬酰胺半富馬酸鹽；阿利克侖半富馬酸鹽

Aliskiren Hemifumarate (Synonyms: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate)

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