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長春西丁; 阿撲長春胺酸乙酯; 長春西汀

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Vinpocetine

產(chǎn)品編號：CL2571 CAS No.：42971-09-5 MDLNo： 分子式：C22H26N2O2 分子量：350.45
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
100 mg 3-5days ￥600.00 登錄后可見
- +
500 mg 3-5days ￥960.00 登錄后可見
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1 g 3-5days ￥1536.00 登錄后可見
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基本信息
英文名稱 Vinpocetine
中文名稱長春西丁; 阿撲長春胺酸乙酯; 長春西汀
CAS號42971-09-5
分子式C22H26N2O2
分子量350.45
外觀White to off-white powder
儲存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Vinpocetine (formerly RGH-4405; AY-27,255; AY27,255, RGH4405, TCV-3B, Cavinton, Intelectol; Ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine which is a natural product extracted from either the seeds of Voacanga africana or the leaves of Vinca minor as well as the lesser periwinkle plant. It is a selective voltage-sensitive sodium channel blocker for the treatment of stroke, vascular dementia and Alzheimer's disease. Vinpocetine has been reported to have a selective and noncompetitive inhibition of Ca2+ PDE and thus regulate cyclic GMP levels in smooth muscle. In addition, vinpocetine has been revealed to inhibit the activities of three resolvable PDE in the cytosol of rat aorta with Ki values of 14±2μM, >1000μM and >1000μM for Ca2+ PDE(+)CaM, cGMP PDE and cAMP PDE, respectively.

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