Capecitabine | RO 09-1978 | Xeloda | CAS 154361-50-9 | DNA/RNA Synthesis inhibitor

規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專(zhuān)享價(jià)	數(shù)量
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規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專(zhuān)享價(jià)

數(shù)量

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基本信息

英文名稱(chēng)	Capecitabine \| RO 09-1978 \| Xeloda
中文名稱(chēng)	卡培他濱
CAS號(hào)	154361-50-9
分子式	C15H22FN3O6
分子量	359.35
外觀(guān)	White to off-white powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

相關(guān)文獻(xiàn)

Capecitabine: A review.

https://doi.org/10.1016/j.clinthera.2005.01.005

PMID: 18077151 DOI: 10.1016/j.ejca.2007.10.023

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卡培他濱

Capecitabine | RO 09-1978 | Xeloda

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