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首頁 > 產(chǎn)品目錄 > 信號(hào)通路 > Microbiology/Virology/ Anti-infection > HIV Protease > 地瑞那韋/達(dá)蘆那韋

地瑞那韋/達(dá)蘆那韋

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Darunavir (TMC114)

產(chǎn)品編號(hào)：CL2205 CAS No.：206361-99-1 MDLNo： 分子式：C??H??N?O?S 分子量：547.66

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規(guī)格	庫存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
200 mg	In-stock	￥300.00	登錄后可見	- +
500 mg	In-stock	￥450.00	登錄后可見	- +
1 g	In-stock	￥750.00	登錄后可見	- +
5 g	In-stock	￥3000.00	登錄后可見	- +

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產(chǎn)品詳情
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基本信息

英文名稱	Darunavir (TMC114)
中文名稱	地瑞那韋/達(dá)蘆那韋
CAS號(hào)	206361-99-1
分子式	C??H??N?O?S
分子量	547.66
外觀	White to off-white powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Darunavir is a drug used to treat HIV infection. It is in the protease inhibitor class. Darunavir is an orally-bioavailable non-peptidic inhibitor of human immunodeficiency virus type 1 (HIV-1) protease that selectively inhibits HIV-1 protease enzyme induced cleavage of gag and gag-pol poly-proteins preventing the maturation of virions and also inhibits the dimerization of HIV-1 protease suppressing proteolytic activity and subsequent replication of HIV-1. Study results have shown that darunavir exhibits potent inhibition against HIV-1 with a value of 50% inhibition concentration IC50 of 0.003 μmol/L in HIV-1 infected MT-2 cells. Darunavir binds to HIV-1 protease with considerably high affinity and fits closely with the substrate envelop leading to its potent ability to inhibit multidrug-resistant HIV strains. Prezista is an OARAC recommended treatment option for treatment-na?ve and treatment-experienced adults and adolescents.

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CL2205

地瑞那韋/達(dá)蘆那韋

206361-99-1 98+% In-stock

￥300.00 200 mg

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