英文名稱 | Ritonavir (ABT 538) |
---|---|
中文名稱 | 利托那韋 |
CAS號 | 155213-67-5 |
分子式 | C37H48N6O5S2 |
分子量 | 720.94 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Ritonavir (ABT 538) |
---|---|
中文名稱 | 利托那韋 |
CAS號 | 155213-67-5 |
分子式 | C37H48N6O5S2 |
分子量 | 720.94 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ritonavir is an inhibitor of HIV-1 protease used to treat HIV infection and AIDS. It is widely used as a booster of other protease inhibitors.
Ritonavir is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases. Ritonavir induces apoptosis.