英文名稱(chēng) | Pravastatin Sodium |
---|---|
中文名稱(chēng) | 普伐他汀鈉 |
CAS號(hào) | 81131-70-6 |
分子式 | C23H35O7.Na |
分子量 | 446.51 |
外觀 | Off-white to Pale purple powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專(zhuān)享價(jià) | 數(shù)量 |
---|---|---|---|---|
10 mg | In-stock | ¥170.00 | 登錄后可見(jiàn) | |
25 mg | In-stock | ¥320.00 | 登錄后可見(jiàn) | |
50 mg | In-stock | ¥450.00 | 登錄后可見(jiàn) | |
100 mg | In-stock | ¥750.00 | 登錄后可見(jiàn) |
英文名稱(chēng) | Pravastatin Sodium |
---|---|
中文名稱(chēng) | 普伐他汀鈉 |
CAS號(hào) | 81131-70-6 |
分子式 | C23H35O7.Na |
分子量 | 446.51 |
外觀 | Off-white to Pale purple powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Pravastatin Sodium is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase Pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells.