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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
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基本信息

英文名稱	Paricalcitol
中文名稱	(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羥基-5,6-二甲基庚-3-烯-2-基)-7-甲基八氫-4H-茚-4-亞基)亞乙基)環(huán)己烷-1,3-二醇；帕立骨化醇
CAS號	131918-61-1
分子式	C27H44O3
分子量	416.64
MDL	MFCD08067734
外觀	White to off-white powder
儲存條件	4°C, protect from light, stored under nitrogen

產(chǎn)品詳情

Paricalcitol, a selective VDR agonist, effectively suppresses PTH mRNA and inhibits parathyroid cell growth, treating secondary hyperparathyroidism in CKD. It's also associated with lower morbidity and improved survival rates compared to other VDRAs, with a favorable side-effect profile. Additionally, paricalcitol exhibits anti-inflammatory effects, potentially beneficial in managing CKD-related inflammation.

相關(guān)文獻(xiàn)

In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/beta-catenin activation.

PMID: 22874762 DOI: 10.1152/ajprenal.00684.2011

PMID: 22800987 DOI: 10.1016/j.jsbmb.2012.06.004

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(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羥基-5,6-二甲基庚-3-烯-2-基)-7-甲基八氫-4H-茚-4-亞基)亞乙基)環(huán)己烷-1,3-二醇；帕立骨化醇

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