英文名稱 | Saxagliptin hydrate | BMS-477118 hydrate |
---|---|
中文名稱 | 沙格列汀水合物 | 沙克列汀水合物 |
CAS號 | 945667-22-1 |
分子式 | C18H25N3O2·H2O |
分子量 | 333.43 | 315.42(free) |
外觀 | White to off-white powder |
英文名稱 | Saxagliptin hydrate | BMS-477118 hydrate |
---|---|
中文名稱 | 沙格列汀水合物 | 沙克列汀水合物 |
CAS號 | 945667-22-1 |
分子式 | C18H25N3O2·H2O |
分子量 | 333.43 | 315.42(free) |
外觀 | White to off-white powder |
Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research.
PMID: 29230196 PMCID: PMC5711777 DOI: 10.3389/fendo.2017.00326
Saxagliptin: A dipeptidyl peptidase-4 inhibitor in the treatment of type 2 diabetes mellitus.
PMID: 22025849 PMCID: PMC3198516 DOI: 10.4103/0976-500X.85934