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規(guī)格	庫存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
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規(guī)格

庫存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

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基本信息

英文名稱	Pictilisib \| GDC-0941 \| RG7321
中文名稱	匹替利司 \| 2-(1H-吲唑-4-基)-6-[[4-(甲基磺?；?-1-哌嗪基]甲基]-4-(4-嗎啉基)噻吩并[3,2-d]嘧啶; 匹替利司
CAS號(hào)	957054-30-7
分子式	C23H27N7O3S2
分子量	513.64
外觀	White to yellow powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

It is currently being investigated for its potential in treating various types of cancer, including solid tumors, breast cancer, and non-Hodgkin’s lymphoma. Pictilisib works by targeting the PI3K pathway, which is often deregulated in cancer cells, leading to uncontrolled cell growth and survival.

相關(guān)文獻(xiàn)

A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.

PMID: 24322983 PMCID: PMC3982380 DOI: 10.1158/0008-5472.CAN-13-0544

PMID: 22588880 PMCID: PMC3384541 DOI: 10.1158/2159-8290.CD-12-0003

PMID: 21994956 DOI: 10.1210/jc.2011-1426

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匹替利司 | 2-(1H-吲唑-4-基)-6-[[4-(甲基磺?；?-1-哌嗪基]甲基]-4-(4-嗎啉基)噻吩并[3,2-d]嘧啶; 匹替利司

957054-30-7 98+%