CP-547632 | PAN-90806 | CP-632 | OSI-632

規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
1 mg	3-5days	￥366.00	登錄后可見	- +
5 mg	3-5days	￥668.00	登錄后可見	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

1 mg

3-5days

￥366.00

登錄后可見

- +

5 mg

3-5days

￥668.00

登錄后可見

- +

基本信息

英文名稱	CP-547632 \| PAN-90806 \| CP-632 \| OSI-632
中文名稱	3-((4-溴-2,6-二氟芐基)氧基)-5-(3-(4-(吡咯烷-1-基)丁基)脲基)異噻唑-4-甲酰胺
CAS號(hào)	252003-65-9
分子式	C20H24BrF2N5O3S
分子量	532.40
MDL	MFCD07772279
外觀	White to light yellow powder
儲(chǔ)存條件	4°C, stored under nitrogen

產(chǎn)品詳情

CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.

相關(guān)文獻(xiàn)

Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.

PMID: 14612527

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