英文名稱 | Sinefungin (Synonyms:Adenosyl-Ornithine; A-9145; Antibiotic 32232RP) |
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中文名稱 | 西奈芬凈 |
CAS號 | 58944-73-3 |
分子式 | C15H23N7O5 |
分子量 | 381.39 |
外觀 | White to yellow powder |
英文名稱 | Sinefungin (Synonyms:Adenosyl-Ornithine; A-9145; Antibiotic 32232RP) |
---|---|
中文名稱 | 西奈芬凈 |
CAS號 | 58944-73-3 |
分子式 | C15H23N7O5 |
分子量 | 381.39 |
外觀 | White to yellow powder |
Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation.