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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
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規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

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基本信息

英文名稱	Vonoprazan Fumarate \| TAK-438
中文名稱	富馬酸沃諾拉贊 \| 富馬酸伏諾拉生\| 1260141-27-2
CAS號(hào)	881681-01-2
分子式	C17H16FN3O2S· C4H4O4
分子量	461.46 \| 345.39 (Free)
外觀	White to off-white powder
儲(chǔ)存條件	4°C, sealed storage, away from moisture and light

產(chǎn)品詳情

Vonoprazan Fumarate, also known as TAK438, is a new medicine for treating acid-related diseases with a novel mechanism of action called potassium-competitive acid blockers (P-CABs) which competitively inhibits the binding of potassium ions to H+,K+-ATPase (also known as the proton pump) in the final step of gastric acid secretion in gastric parietal cells. TAKECAB provides a strong and sustained acid secretion inhibitory effect.

相關(guān)文獻(xiàn)

Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).

PMID: 22512618 DOI: 10.1021/jm300318t

PMID: 20624992 DOI: 10.1124/jpet.110.170274

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富馬酸沃諾拉贊 | 富馬酸伏諾拉生| 1260141-27-2

Vonoprazan Fumarate | TAK-438

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