英文名稱 | Azvudine | RO-0622 | FNC |
---|---|
中文名稱 | 阿茲夫定 |
CAS號 | 1011529-10-4 |
分子式 | C9H11FN6O4 |
分子量 | 286.22 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Azvudine | RO-0622 | FNC |
---|---|
中文名稱 | 阿茲夫定 |
CAS號 | 1011529-10-4 |
分子式 | C9H11FN6O4 |
分子量 | 286.22 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Azvudine (RO-0622) is a novel nucleoside reverse transcriptase inhibitor with antiviral activity against human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV), potently inhibits HIV-1 (EC50 range 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).
PMID: 25144636 PMCID: PMC4140803 DOI: 10.1371/journal.pone.0105617